Mild Bioconjugation Through the Oxidative Coupling of ortho??Aminophenols and Anilines with Ferricyanide

…, C Netirojjanakul, K El Muslemany…

Index: Obermeyer, Allie C.; Jarman, John B.; Netirojjanakul, Chawita; El Muslemany, Kareem; Francis, Matthew B. Angewandte Chemie - International Edition, 2014 , vol. 53, # 4 p. 1057 - 1061 Angew. Chem., 2014 , vol. 126, # 4 p. 1075 - 1079

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Citation Number: 12

Abstract

Abstract Using a small-molecule-based screen, ferricyanide was identified as a mild and efficient oxidant for the coupling of anilines and o-aminophenols on protein substrates. This reaction is compatible with thiols and 1, 2-diols, allowing its use in the creation of complex ...