Efficient Preparation of Biologically Important 1, 2-Amino Alcohols
P Gupta, A Rouf, BA Shah, D Mukherjee…
Index: Gupta, Pankaj; Rouf, Abdul; Shah, Bhahwal A.; Mukherjee, Debaraj; Taneja, Subhash C. Synthetic Communications, 2013 , vol. 43, # 4 p. 505 - 519
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Abstract
The selective reduction of protected amino ketone derivatives is preferred because of their good stability. [ 8 8. Fujisawa , T. ; Hayashi , H. ; Kishioka , Y. Enantioselective synthesis of optically pure amino alcohol derivatives by yeast reduction . Chem. Lett. 1987 , 129 – 132 . [CrossRef], [Web of Science ®] View all references ] However, their precursors (amino ketones) are difficult to isolate as free amines because of the formation of Schiff bases. ...
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