Synthesis and Biological Evaluation of New 3??Aralkylamino??2??aryl??2H??1, 2, 4??pyridothiadiazine 1, 1??dioxides as Potential CCK??Receptor Ligands
…, T PODONA, D CAIGNARD, P RENARD…
Index: De Tullio, Pascal; Pirotte, Bernard; Neven, Philippe; Masereel, Bernard; Dewalque, Daniel; Diouf, Ousmane; Podona, Tchao; Caignard, Daniel; Renard, Pierre; Delarge, Jacques Journal of Pharmacy and Pharmacology, 1997 , vol. 49, # 5 p. 463 - 471
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Abstract
Abstract A series of 2-aralkyl-4H-pyridothiadiazine 1, 1-dioxides and 3-aralkylamino-2-aryl- 2H-pyrido [4, 3-e]-1, 2, 4-thiadiazine 1, 1-dioxides structurally related to quinazolinone CCK receptor antagonists were synthesized and evaluated as CCK-A and CCK-B receptor ligands.
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