Radiosynthesis and evaluation of [18F] Selectfluor bis (triflate)

…, A Kirjavainen, S Forsback, G Sandford…

Index: Teare, Harriet; Robins, Edward G.; Kirjavainen, Anna; Forsback, Sarita; Sandford, Graham; Solin, Olof; Luthra, Sajinder K.; Gouverneur, Veronique Angewandte Chemie - International Edition, 2010 , vol. 49, # 38 p. 6821 - 6824

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Citation Number: 78

Abstract

Positron (β+) emission tomography (PET) is a noninvasive molecular imaging technique that allows for the invivo investigation of physiological processes.[1] As a radioisotope, fluorine- 18 benefits from an advantageous half-life (109.7 min), a clean decay process (97% β+ emission), and a short β+ trajectory, which is a property that enables the acquisition of high- resolution images. The global use of the radiotracer [18F]-2-fluoro-2-deoxy-d-glucose has ...