NAD (P)+-NAD (P) H models. 55. Transition metal catalyzed reduction of organic halides: high selectivity for reductive dehalogenation

S Yasui, K Nakamura, M Fujii…

Index: Yasui, Shinro; Nakamura, Kaoru; Fujii, Masayuki; Ohno, Atsuyoshi Journal of Organic Chemistry, 1985 , vol. 50, # 18 p. 3283 - 3287

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Citation Number: 27

Abstract

Various types of aryl, benzyl, vinyl, phenacyl, and allyl halides were subjected to reaction with N-benzyl-1, 4dihydronicotinamide (BNAH), in the presence of a catalytic amount of chlorotris (triphenylphmphine) rhodium (I) or palladium (I1) acetate. The carbon-halogen bonds in these compounds were selectively reduced to the carbon-hydrogen bonds in moderate to excellent yield. This new kind of reduction system has synthetic advantages ...