A Novel Synthesis of Highly Substituted Perhydropyrrolizines, Perhydroindolizines, and Pyrrolidines: Inhibition of the Peptidyl??Prolyl cis/trans Isomerase (PPIase) Pin1

R Siegrist, M Zürcher, C Baumgartner…

Index: Helvetica Chimica Acta, , vol. 90, # 2 p. 217 - 259

Full Text: HTML

Citation Number: 15

Abstract

... (+)-33c H MeO naphthalen-2-yl PhCH2 P(O)(OH)2 9 (À)-38c H MeO naphthalen-2-yl PhCH2 H inactive a) Uncertainties in Ki : Æ10 – 20%. b) Piperonyl=(1,3-benzodioxol- 5-yl)methyl. Helvetica Chimica Acta – Vol. 90 (2007) 230 Page 15. ...

Related Articles:

A practical stereoselective synthesis of (2S, 3S)-3-hydroxyleucine

[Tetrahedron Letters, , vol. 36, # 39 p. 7031 - 7034]

Total synthesis of balanol

[Journal of the American Chemical Society, , vol. 116, # 18 p. 8402 - 8403]

Synthesis of d-Abrines by Palladium-catalyzed Reaction of ortho-Iodoanilines with N-Boc-N-methylalanyl-substituted Acetaldehyde and Acetylene

[Organic Letters, , vol. 15, # 10 p. 2474 - 2477]

Synthesis of 3-aminochroman derivatives by radical cyclization

[Organic Letters, , vol. 5, # 23 p. 4253 - 4256]

Syntheses of acyclic analogues of kainoids and neuroexcitatory activity

[Tetrahedron Letters, , vol. 30, # 29 p. 3799 - 3802]

More Articles...