Reaction between Δ 2-oxazolin-5-ones and nitrosobenzene. Formation of 1, 2, 4-oxadiazolines
H Rodríguez, H Pavez, A Márquez, P Navarrete
Index: Rodriguez, H.; Pavez, H.; Marquez, A.; Navarrete, P. Tetrahedron, 1983 , vol. 39, # 1 p. 23 - 27
Full Text: HTML
Citation Number: 14
Abstract
2, 4-diphenyl-and 2-p-methylphenyl-4-phenyl-Δ2-oxazolin-5-ones react at 80–110° C with nitrosobenzene to give benzamidines. However, reactions conducted at room temperature afford in high yield, the heretofore undescribed Δ4-1, 2, 4-oxadiazolin-3-carboxylic acids by regiospecific 1, 3-dipolar cycloaddition. Thermal decomposition of the oxadiazolinecarboxylic acids gives the corresponding benzamidines.
Related Articles:
[Mendes, Eduarda; Furtado, Tania; Neres, Joao; Iley, Jim; Jarvinen, Tomi; Rautio, Jarkko; Moreira, Rui Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 3 p. 809 - 816]
[Mendes, Eduarda; Furtado, Tania; Neres, Joao; Iley, Jim; Jarvinen, Tomi; Rautio, Jarkko; Moreira, Rui Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 3 p. 809 - 816]
Photochemical cleavage and release of carboxylic acids from α-keto amides
[Ma, Chicheng; Steinmetz, Mark G.; Kopatz, Erica J.; Rathore, Rajendra Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4431 - 4442]
Photochemical cleavage and release of carboxylic acids from α-keto amides
[Ma, Chicheng; Steinmetz, Mark G.; Kopatz, Erica J.; Rathore, Rajendra Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4431 - 4442]
Photochemical cleavage and release of carboxylic acids from α-keto amides
[Ma, Chicheng; Steinmetz, Mark G.; Kopatz, Erica J.; Rathore, Rajendra Journal of Organic Chemistry, 2005 , vol. 70, # 11 p. 4431 - 4442]