A Three??Way Switchable Process for Suzuki Cross??Coupling, Hydrodehalogenation, or an Assisted Tandem Hydrodehalogenation and Suzuki Cross??Coupling …
AH Sandtorv, HR Bjørsvik
Index: Sandtorv, Alexander H.; Bjorsvik, Hans-Rene Advanced Synthesis and Catalysis, 2013 , vol. 355, # 16 p. 3231 - 3243
Full Text: HTML
Citation Number: 8
Abstract
Abstract: A three-way switchable Pd-catalyzed and microwave assisted process appropriate for selective arylation or hydrodehalogenation of the imidazole backbone was discovered and entirely optimized. The “arylation switch position” was adapted and optimized for the synthesis of 4, 5-diaryl-1H-imidazoles, while the “hydrodehalogenation switch position” was used for the preparation of 4 (5)-iodo-1H-imidazole. The hydrodehalogenation and the ...
Related Articles:
[Bellina, Fabio; Cauteruccio, Silvia; Rossi, Renzo Journal of Organic Chemistry, 2007 , vol. 72, # 22 p. 8543 - 8546]
[Song, Zhiguo; DeMarco, Anthony; Zhao, Mangzhu; Corley, Edward G.; Thompson, Andrew S.; McNamara, James; Li, Yulan; Rieger, Dale; Sohar, Paul; Mathre, David J.; Tschaen, David M.; Reamer, Robert A.; Huntington, Martha F.; Ho, Guo-Jie; Tsay, Fuh-Rong; Emerson, Khateeta; Shuman, Richard; Grabowski, Edward J. J.; Reider, Paul J. Journal of Organic Chemistry, 1999 , vol. 64, # 6 p. 1859 - 1867]
[Amemiya, Yoshiya; Miller, Duane D.; Hsu, Fu-Lian Synthetic Communications, 1990 , vol. 20, # 16 p. 2483 - 2489]
A two-step synthesis of imidazoles from aldehydes via 4-tosyloxazolines
[Heterocycles, , vol. 39, # 1 p. 139 - 154]
A new synthesis of unsubstituted, 4 (5), and 4, 5-substituted 1H-imidazoles.
[Tetrahedron Letters, , vol. 27, # 41 p. 5019 - 5020]