Process development for ABT-472, a benzimidazole PARP inhibitor
JH Barkalow, J Breting, BJ Gaede…
Index: Organic Process Research and Development, , vol. 11, # 4 p. 693 - 698
Full Text: HTML
Citation Number: 20
Abstract
... Organic Process Research & Development. ... The process was successfully scaled up to provide 8.5 kg of final product of >99% purity in 33% yield ... 13 Calorimetry during the direct addition procedure showed an exotherm of −140 kJ/mol, consistent with the calculated exotherm for ...
Related Articles:
Synthesis, Characterization and Thermal Properties of Some New Azopolyimides
[Asian Journal of Chemistry, , vol. 24, # 7 p. 3033 - 3038]
Justus Liebig's Annalen Der Chemie. Über die Einwirkung des Ozons auf organische Verbindungen
[Justus Liebigs Annalen der Chemie, , vol. 160, p. 64 Chemische Berichte, , vol. 11, p. 393 Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 10, p. 196 Justus Liebigs Annalen der Chemie, , vol. 208, p. 230 Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, , vol. 10, p. 192 Justus Liebigs Annalen der Chemie, , vol. 208, p. 225]
Synthetic approaches to cyclohept [f] indenes
[Journal of Organic Chemistry, , vol. 32, p. 42 - 49]
Synthetic approaches to cyclohept [f] indenes
[Journal of Organic Chemistry, , vol. 32, p. 42 - 49]
Justus Liebig's Annalen Der Chemie. Über die Einwirkung des Ozons auf organische Verbindungen
[Justus Liebigs Annalen der Chemie, , vol. 38, p. 14 Justus Liebigs Annalen der Chemie, , vol. 42, p. 215 Justus Liebigs Annalen der Chemie, , vol. 41, p. 107,110]