Tetrahedron Letters

Ligand effects in enantioface differentiating 1, 4 addition to 1, 3 diphenyl-2 propen-1 one

F Leyendecker, F Jesser, D Laucher

Index: Leyendecker, Francois; Jesser, Francis; Laucher, Dominique Tetrahedron Letters, 1983 , vol. 24, # 33 p. 3513 - 3516

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Citation Number: 31

Abstract

Abstract The extent of enantiomeric excess in the β-methylation of chalcone by chiral cuprates is shown to depend strongly on small structural modifications of the ligands, all of which are derived from the basic carbon framework of L-prolinol. Enantiomeric excesses up to 88% have been realised.

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