Tetrahedron letters

A general protocol for the preparation of phospholipids via phosphite coupling

SF Martin, JA Josey

Index: Martin, Stephen F.; Josey, John A. Tetrahedron Letters, 1988 , vol. 29, # 30 p. 3631 - 3634

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Citation Number: 37

Abstract

Abstract A method for the facile preparation of a variety of phospholipids and their derivatives has been developed that utilizes a highly efficient phosphite coupling procedure for the synthesis of a phosphite triester, which may then be readily transformed into the corresponding phosphate diester by sequential oxidation and O-deprotection.