Transition state analogue discrimination by related purine nucleoside phosphorylases

EA Taylor Ringia, PC Tyler, GB Evans…

Index: Journal of the American Chemical Society, , vol. 128, # 22 p. 7126 - 7127

Full Text: HTML

Citation Number: 32

Abstract

... Journal of the ... Soc. , 2006, 128 (22), pp 7126–7127. DOI: 10.1021/ja061403n. Publication Date (Web): May 12, 2006. Copyright © 2006 American Chemical Society. ... Chemically stable analogues of a transition state complex are predicted to convert the energy of enzymatic rate ...

Synthesis and biological evaluation of potential 5-HT 7 receptor PET radiotracers

[European Journal of Medicinal Chemistry, , vol. 46, # 8 p. 3455 - 3461]

A novel, potent, and selective 5-HT7 antagonist:(R)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl) pyrrolidine-1-sulfonyl) phenol (SB-269970)

[Journal of Medicinal Chemistry, , vol. 43, # 3 p. 342 - 345]

Endomorphin-1 analogues containing β-proline are μ-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance

[Journal of Medicinal Chemistry, , vol. 45, # 12 p. 2571 - 2578]