Binding activity of substituted benzyl derivatives of chloronicotinyl insecticides to housefly??head membranes, and its relationship to insecticidal activity against the …

H Nishiwaki, Y Nakagawa, DY Takeda…

Index: Nishiwaki, Hisashi; Nakagawa, Yoshiaki; Takeda, David Y.; Okazawa, Atsushi; Akamatsu, Miki; Miyagawa, Hisashi; Ueno, Tamio; Nishimura, Keiichiro Pest Management Science, 2000 , vol. 56, # 10 p. 875 - 881

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Citation Number: 26

Abstract

Abstract Variously substituted benzyl derivatives of chloronicotinyl insecticides were synthesized with a wide range of substituents including halogens, NO 2, CN, CF 3 and small alkyl and alkoxy groups at the ortho, meta and para positions, as well as multiple-substituted benzyl analogues. Their binding activity to the α-bungarotoxin binding site in housefly (Musca domestica) head membrane preparations was measured. Among the compounds ...