Design and synthesis of imidazoline derivatives active on glucose homeostasis in a rat model of type II diabetes. 2. Syntheses and biological activities of 1, 4-dialkyl-, …

G Le Bihan, F Rondu, A Pelé-Tounian…

Index: Journal of Medicinal Chemistry, , vol. 42, # 9 p. 1587 - 1603

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Citation Number: 66

Abstract

... Journal of Medicinal Chemistry. ... 14,15. In a previous paper, 16 we described the syntheses and pharmaceutical evaluation of new antihyperglycemic 1,4-disubstituted-2-(4',5'-dihydro-1'H-imidazol- 2'-yl)- piperazines having the following general formula: These compounds ...

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