Pyrido [2, 3-d] pyrimidin-5-ones: A Novel Class of Antiinflammatory Macrophage Colony-Stimulating Factor-1 Receptor Inhibitors†

H Huang, DA Hutta, JM Rinker, H Hu…

Index: Swindell, Charles S.; Duffy, Ruth H. Heterocycles, 1986 , vol. 24, # 12 p. 3373 - 3377

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Citation Number: 31

Abstract

... Volume: Page: ... figure Chart 1. FMS Inhibitors. We have identified several classes of novel FMS inhibitors: arylamides (8),(23) 3,4,6-substituted 2-quinolones (9),(24) and pyrido ... e) Et 3 N, CH 2 Cl 2 , rt; (f) m-CPBA, CH 2 Cl 2 , rt; (g) arylamine, i-PrOH, 90 °C; (h) R 1 ...