One-pot approach for the synthesis of 2-aryl benzothiazoles via a two-component coupling of gem-dibromomethylarenes and o-aminothiophenols

…, V Kambappa, M Umashankara, KS Rangappa

Index: Siddappa, Chandrappa; Kambappa, Vinaya; Umashankara, Muddegowda; Rangappa, Kanchugarakoppal S. Tetrahedron Letters, 2011 , vol. 52, # 42 p. 5474 - 5477

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Citation Number: 17

Abstract

One-pot synthesis of 2-aryl benzothiazoles from gem-dibromomethylarenes using 2- aminoarylthiols is described. Benzothiazoles were obtained in high chemical yields under mild conditions. This transformation would facilitate synthesis by short reaction times, large- scale synthesis, easy and quick isolation of the products, which are the main advantages of this procedure.

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