Kinetic modelling of synthesis of N-aminopiperidine from hydroxylamine-O-sulfonique acid and piperidine

E Labarthe, AJ Bougrine, V Pasquet, H Delalu

Index: Labarthe; Bougrine; Pasquet; Delalu Kinetics and Catalysis, 2012 , vol. 53, # 1 p. 25 - 35

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Citation Number: 3

Abstract

Abstract A new route to synthesize N-aminopiperidine (NAPP) from hydroxylamine-O- sulfonique acid (HOSA) and piperidine was described. Kinetics of the reaction was investigated to optimize the conditions of the synthesis. Since the reaction is fast, this study was carried out in a diluted medium (10− 3 to 10− 2 mol/l). To determine the concentration of the reaction product, NAPP was allowed to react with formaldehyde and the product was ...