Novel synthesis of 2-oxo-4-phenyl-3-butynoic acid, a new inhibitor and alternate substrate of pyruvate decarboxylase
CC Chiu, F Jordan
Index: Journal of Organic Chemistry, , vol. 59, # 19 p. 5763 - 5766
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Citation Number: 23
Abstract
... (2) For a review of the chemistry of 2 ... The combined organic layer was dried and concentrated to a crude product which was purified by recrystallization from toluene to afford 159 mg of 1 (95%) as yellow needles: mp 80- 81 "C; lH NMR (CDCIJI'MS) 6 7.31-7.61 (m, 5 ... (t, 3, J = 7 Hz ...
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