Oxytocin analogues with amide groups substituted by tetrazole groups in position 4, 5 or 9

M Manturewicz, Z Grzonka, L Borovickova…

Index: Manturewicz; Grzonka Polish Journal of Chemistry, 2007 , vol. 81, # 12 p. 2121 - 2131

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Citation Number: 6

Abstract

Eleven oxytocin analogues substituted in position 4, 5 or 9 by tetrazole analogues of amino acids were prepared using solid-phase peptide synthesis method and tested for rat uterotonic in vitro and pressor activities, as well as for their affinity to human oxytocin