Further studies on sodium borohydride-polyethylene glycol 400 as a novel reducing system

E Santaniello, P Ferraboschi, A Fiecchi…

Index: Santaniello, Enzo; Ferraboschi, Patrizia; Fiecchi, Alberto; Grisenti, Paride; Manzocchi, Ada Journal of Organic Chemistry, 1987 , vol. 52, # 4 p. 671 - 674

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Citation Number: 7

Abstract

furan solution of Na (PEG), BH, was tested for selective reduction of phthalic anhydride (5) to phthalide (6). Indeed, an intriguing situation was evident from the results of this reduction by means of Na (PEG)* BH, at different temperatures (Table 11). At room temperature, no formation of phthalide (6) was observed and a mixture of phthalic acid (7a)(identified as its dimethyl ester, 34%) and a monoester of phthalic acid with PEG (compound 7b, 22% yield ...

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