Practical synthesis of maleimides and coumarin-linked probes for protein and antibody labelling via reduction of native disulfides

HY Song, MH Ngai, ZY Song, PA MacAry…

Index: Organic and Biomolecular Chemistry, , vol. 7, # 17 p. 3400 - 3406

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Citation Number: 57

Abstract

... Maleimide-incorporated probes are used extensively in biology and chemistry. ... In particular, 6 can efficiently label cysteine-bearing biomolecules on peptides or proteins, even ... antibody material to retain their stability and function for additional labelling, biomolecular and cellular ...