Synthesis and Antimicrobial Activity of Some New 1, 4-Benzothiazine Containing Thiosemicarbazides and 1, 3, 4-Oxadiazole Derivatives

…, RJ Kapade, PS Girase, BR Chaudhari

Index: Khairnar, Bhikan J; Salunke, Rahul S; Patil, Premchand B; Patil, Sanjay A; Kapade, Rajeshwar J; Girase, Pravin S; Chaudhari, Bhata R E-Journal of Chemistry, 2012 , vol. 9, # 1 p. 318 - 322

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Citation Number: 2

Abstract

A series of novel 3-methyl-7-substituted-4H, 4-benzothiazine-2-carbohydrazide (3a-e) and corresponding thiosemicarbazides (4-aq); 2-[3-methyl-7-substituted-4H-1, 4-benzothiazine- 2-yl]-N-(aryl) hydrazine carbothiamide have been synthesized. The thiosemicarbazide when cyclized with iodine via intramolecular cyclisation gave benzothiazonyl oxadiazoles (5-aq); 5- (3-methyl-7-substitued-4H-1, 4-benzothiazin-2-yl)-N—aryl-1, 3, 4-oxadiazol-2-amine and ...

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