Syntheses of alkyl (E)-(1-aryl-2-pyrrolidinylidene) acetates
JP Michael, GD Hosken, AS Howard
Index: Michael,J.P.; Hosken,G.D.; Howard,A.S. Tetrahedron, 1988 , vol. 44, p. 3025
Full Text: HTML
Citation Number: 34
Abstract
Two methods for the synthesis of the title compounds [3] are presented. The first, and less satisfactory, method uses the sulphide contraction, which involves salt formation between alkyl bromoacetates and N-arylpyrrolidine-2-thiones [2] followed by sulphur extrusion. By- products include N-arylpyrrolidin-2-ones [1] and 3-alkoxycarbonylmethylpyrrolidine-2- thiones [5]. A better route is by way of condensation between ethyl 6-chloro-3- ...
Related Articles:
Amino acid-mediated Goldberg reactions between amides and aryl iodides
[Deng, Wei; Wang, Ye-Feng; Zou, Yan; Liu, Lei; Guo, Qing-Xiang Tetrahedron Letters, 2004 , vol. 45, # 11 p. 2311 - 2315]
[Yamamoto, Takakazu; Kurata, Yasundo Canadian Journal of Chemistry, 1983 , vol. 61, p. 86 - 91]
Hydroformylation of bisolefinic amine derivatives catalyzed by cobalt and rhodium
[Garst, Michael E.; Lukton, David Journal of Organic Chemistry, 1981 , vol. 46, # 22 p. 4433 - 4438]
[Wang, Eng Chi; Lin, Huey-Jen Heterocycles, 1998 , vol. 48, # 3 p. 481 - 489]
Properties of bis (trifluoroacetoxy) borane as a reducing agent of organic compounds
[Maryanoff, Bruce E.; McComsey, David F.; Nortey, Samuel O. Journal of Organic Chemistry, 1981 , vol. 46, # 2 p. 355 - 360]