Bioactive oleanane-type saponins from the rhizomes of Anemone taipaiensis

XY Wang, H Gao, W Zhang, Y Li, G Cheng…

Index: Wang, Xiao-Yang; Gao, Hui; Zhang, Wei; Li, Yuan; Cheng, Guang; Sun, Xiao-Li; Tang, Hai-Feng Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 20 p. 5714 - 5720

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Citation Number: 9

Abstract

Abstract Investigation of the n-BuOH extract of the rhizomes of Anemone taipaiensis led to the isolation of five new oleanane-type triterpenoid saponins (1–5), together with seven known saponins (6–12). Their structures were determined by the extensive use of 1 D and 2 D NMR experiments along with ESIMS analyses and acid hydrolysis. The aglycone of 1, 2 and 4 was determined as siaresinolic acid, which was reported in this genus for the first ...