Tetrahedron

Isolation, synthesis, and biological activity of biphenyl and m-terphenyl-type compounds from Dictyostelium cellular slime molds

H Kikuchi, Y Matsuo, Y Katou, Y Kubohara, Y Oshima

Index: Kikuchi, Haruhisa; Matsuo, Yusuke; Katou, Yasuhiro; Kubohara, Yuzuru; Oshima, Yoshiteru Tetrahedron, 2012 , vol. 68, # 43 p. 8884 - 8889

Full Text: HTML

Citation Number: 15

Abstract

From the fruiting bodies of Dictyostelium polycephalum, we obtained four aromatic compounds: dictyobiphenyl A (1) and B (2) and dictyoterphenyl A (3) and B (4). The synthesis of 1–4 was performed to confirm the structures and obtain sufficient material for biological evaluation. Compound 3 was the first example of nitrogen-containing natural m- terphenyls, and the isolation of novel classes of compounds such as 3 shows that cellular ...