Synthesis of Pyridines and Pyrazines Using an Intramolecular Hydroamination??Based Reaction Sequence

…, EJF Bilodeau, AM Beauchemin

Index: Rizk, Toni; Bilodeau, Eric J.-F.; Beauchemin, Andre M. Angewandte Chemie - International Edition, 2009 , vol. 48, # 44 p. 8325 - 8327

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Citation Number: 36

Abstract

The prevalence and diversity of aromatic nitrogen heterocycles found in natural products and used in medicinal chemistry continues to fuel the development of new methods and strategies for their syntheses.[1] Recently, advances in amination chemistry (eg, CÀH insertions, metal-catalyzed annulations, Buchwald–Hartwig cross-couplings, oxidative aminations, hydroaminations) have enabled routes to diverse aromatic ring systems and ...

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