Chemical communications

One-pot synthesis of benzolactones and lactams via a cobalt-catalyzed regioselective [2+ 2+ 2] cocyclotrimerization of alkynyl alcohols and amines with propiolates

HT Chang, M Jeganmohan, CH Cheng

Index: Chang, Hong-Tai; Jeganmohan, Masilamani; Cheng, Chien-Hong Chemical Communications, 2005 , # 39 p. 4955 - 4957

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Citation Number: 19

Abstract

The transition metal catalyzed [2 + 2 + 2] cycloaddition reaction of unsaturated molecules is an efficient method to construct six-membered cyclic compounds with the formation of three new carbon–carbon bonds. 1 This cycloaddition reaction has been known for the past few decades. Of these cycloadditions, the intramolecular and partially intermolecular modes of cyclotrimerization have been established as powerful synthetic methods. 2 However, completely ...