Synthesis of pterostilbene and resveratrol carbamate derivatives as potential dual cholinesterase inhibitors and neuroprotective agents
W Yuan, Z Shang, X Qiang, Z Tan, Y Deng
Index: Yuan, Wen; Shang, Zhipei; Qiang, Xiaoming; Tan, Zhenghuai; Deng, Yong Research on Chemical Intermediates, 2014 , vol. 40, # 2 p. 787 - 800
Full Text: HTML
Citation Number: 6
Abstract
Abstract Pterostilbene and resveratrol carbamate derivatives were designed and synthesized by use of a multi-target directed drug-design strategy. Their acetylcholinesterase and butylcholinesterase inhibitory activity and neuroprotective effects against hydrogen peroxide-induced PC12 cell injury were evaluated in vitro. The results indicated that some of the compounds had dual inhibitory potency against ...
Related Articles:
An improved one-pot cost-effective synthesis of N, N-disubstituted carbamoyl halides and derivatives
[Adeppa; Rupainwar; Misra, Krishna Canadian Journal of Chemistry, 2010 , vol. 88, # 12 p. 1277 - 1280]
[Hoshino, Osamu; Saito, Keiji; Ishizaki, Miyuki; Umezawa, Bunsuke Synthetic Communications, 1987 , vol. 17, # 16 p. 1887 - 1892]
Journal of the American Pharmaceutical Association (1912–1939)
[Journal of the American Pharmaceutical Association (1912-1977), , vol. 46, p. 290 Journal of the Chemical Society, , p. 313 Journal of the Chemical Society, , p. 5041 Chemicke Listy, , vol. 46, p. 762,764 Collection of Czechoslovak Chemical Communications, , vol. 18, p. 870,876 Chem.Abstr., , p. 12302]
Selective cleavage of N-benzyl-protected secondary amines by triphosgene
[Journal of Organic Chemistry, , vol. 68, # 2 p. 613 - 616]
Importance of the lipophilic group in carbamates having histamine H3-receptor antagonist activity.
[Pharmazie, , vol. 55, # 5 p. 349 - 355]