Synthetic Communications

A mild and convenient oxidation of aryl nitriles to aryl amides by aqueous sodium perborate

KL Reed, JT Gupton, TL Solarz

Index: Reed, Kathryn L.; Gupton, John T.; Solarz, Traci L. Synthetic Communications, 1990 , vol. 20, # 4 p. 563 - 571

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Citation Number: 23

Abstract

Abstract A series of benzonitriles has been reacted with sodium perborate in water and a cosolvent to produce the corresponding amides in good yield. The procedure is a mild and convenient alternative for the synthesis of aryl amides.

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