Facile synthesis of l-Dopa tert-butyl ester by catalytic enantioselective phase-transfer alkylation
T Ooi, M Kameda, H Tannai, K Maruoka
Index: Tetrahedron Letters, , vol. 41, # 43 p. 8339 - 8342
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Citation Number: 75
Abstract
... Tetrahedron Letters. ... acids can be synthesized in an enantiomerically pure form by the phase-transfer catalytic alkylation of substrate 2. In this letter, we wish to ... alkylation of 2 with benzyl bromide 3 (R 1 =OBn) (1.2 equiv.) 3 in toluene–50% KOH aqueous solution (volume ratio=3 ...
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