Metabolism-guided discovery of a potent and orally bioavailable urea-based calcimimetic for the treatment of secondary hyperparathyroidism

PM Wehn, PE Harrington, TJ Carlson, J Davis…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 24 p. 6625 - 6628

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Abstract

... Bioorganic & Medicinal Chemistry Letters. ... b Department of Medicinal Chemistry, Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA; c Department of Pharmacokinetics and Drug ... Jameson (Eds.), Harrison's Principles of Internal Medicine (16th ed.)Vol. ...

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