New method for selective monofluorination of aromatics using silver difluoride

A Zweig, RG Fischer, JE Lancaster

Index: Zweig, Arnold; Fischer, Robert G.; Lancaster, John E. Journal of Organic Chemistry, 1980 , vol. 45, # 18 p. 3597 - 3603

Full Text: HTML

Citation Number: 34

Abstract

Fluorobenzene is obtained in 61% yield from reaction of a solution of benzene in n-hexane with solid argentic fluoride (AgF2.). The AgFz acta as both a strong oxidant and the fluoride source. Cobaltic fluoride provides only low (43%) yields of fluorobenzene under similar conditions. The predominant reaction of benzene solutions with AgFz appears to proceed by a process involving initial electrophilic oxidative cis addition of two fluorine atoms from the ...

Related Articles:

Tetraphenylphosphonium bromide catalyzed fluorodenitrations and fluorodesulfonylations. Efficient syntheses of m-fluoroaromatic compounds.

[Yazawa, Naoto; Suzuki, Hiroshi; Yoshida, Yasuo; Furusawa, Osamu; Kimura, Yoshikazu Chemistry Letters, 1989 , p. 2213 - 2216]

Synthesis of functionalized aryl fluorides using organolithium reagents in flow microreactors

[Nagaki, Aiichiro; Uesugi, Yuki; Kim, Heejin; Yoshida, Jun-Ichi Chemistry - An Asian Journal, 2013 , vol. 8, # 4 p. 705 - 708]

Ruthenium-catalyzed one-pot synthesis of primary amides from aldehydes in water

[Garcia-Alvarez, Rocio; Diaz-Alvarez, Alba E.; Crochet, Pascale; Cadierno, Victorio RSC Advances, 2013 , vol. 3, # 17 p. 5889 - 5894]

Synthesis of 3, 4-difluorobenzonitrile and monofluorobenzonitriles by means of halogen-exchange fluorination

[Suzuki, Hiroshi; Kimura, Yoshikazu Journal of Fluorine Chemistry, 1991 , vol. 52, # 3 p. 341 - 351]

The cyanation of aromatic halides catalyzed by nickel (0) complexes generated in situ. I. General scope and limitations.

[Sakakibara, Yasumasa; Okuda, Fumio; Shimobayashi, Akira; Kirini, Kunihiko; Sakai, Mutsuji; et al. Bulletin of the Chemical Society of Japan, 1988 , vol. 61, p. 1985 - 1990]

More Articles...