Haloarene derivatives of carbamazepine with reduced bioactivation liabilities: 2-monohalo and 2, 8-dihalo derivatives

EC Elliott, SL Regan, JL Maggs…

Index: Schweim, Harald G. Archiv der Pharmazie (Weinheim, Germany), 1987 ,  vol. 320,  # 5  p. 430 - 437

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Citation Number: 7

Abstract

... Volume: Page ... is used widely for the treatment of epilepsy, trigeminal neuralgia, and certain neuropsychiatric conditions,(5) conforms with ... group might be expected to prevent dehalogenation via an N-oxidation that generates a p-benzoquinoneimine intermediate ...