Preparation and evaluation of sulfur-containing metal chelators

…, Ø Rist, S Hansen, LO Gerlach, T Högberg…

Index: Clavier, Sylvain; Rist, ystein; Hansen, Stina; Gerlach, Lars-Ole; Hoegberg, Thomas; Bergman, Jan Organic and Biomolecular Chemistry, 2003 , vol. 1, # 23 p. 4248 - 4253

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Citation Number: 21

Abstract

With a view to probe the structure and function of G-protein coupled receptors the synthesis of functionalized 8-mercaptoquinoline derivatives and 2-(2-pyridyl) thiophenol was achieved. A fluorescence-based method for determining the affinity of these metal chelators toward zinc ions was developed.