Organic letters

N-formylation of amines by methanol activation

N Ortega, C Richter, F Glorius

Index: Ortega, Nuria; Richter, Christian; Glorius, Frank Organic Letters, 2013 , vol. 15, # 7 p. 1776 - 1779

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Citation Number: 51

Abstract

In recent years, great advances have been made in the area of alcohol activation. A remarkable example is the acceptorless dehydrogenative coupling of primary alcohols (ADC) to give the corresponding esters, which is an environmentally friendly and atom-efficient alternative to the classic approach based on the esterification of carboxylic acids. Established methods typically require activation of the carboxylic acid or the use of stoichiometric amounts of ...

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