Reactions of 4-chloro-1-nitrobenzene with (3-chloro-4-methoxyphenyl) acetonitrile and (3, 4-dimethoxyphenyl) acetonitrile; Synthesis of 8-chloro-1-methyl (and …

…, J Holubek, M Buděšínský, M Ryska…

Index: Vejdelek, Zdenek; Holubek, Jiri; Budesinsky, Milos; Ryska, Miroslav; Svatek, Emil; Protiva, Miroslav Collection of Czechoslovak Chemical Communications, 1988 ,  vol. 53,  # 2  p. 361 - 372

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Citation Number: 2

Abstract

Abstract Reactions of 4-chloro-1-nitrobenzene with (3-chloro-4-methoxyphenyl) acetonitrile and (3, 4-dimethoxyphenyl) acetonitrile in methanolic potassium hydroxide gave the corresponding 3-aryl-5-chloro-2, 1-benzisoxazoles Ia and Ib in good yields; compounds Va, Vb, VI-VIII and X were isolated as by-products and identified by means of spectra. Compounds Ia and Ib were transformed in five steps to the title compounds XVab and ...