Tetrahedron letters

Highly efficient total synthesis of manoalide and seco-manoalide via Pd (0) catalyzed coupling of allyhalide with CO and 2-silyl-4-stannylfuran

S Katsumura, S Fujiwara, S Isoe

Index: Katsumura, Shigeo; Fujiwara, Shinya; Isoe, Sachihiko Tetrahedron Letters, 1988 ,  vol. 29,  # 10  p. 1173 - 1176

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Citation Number: 42

Abstract

Abstract Total synthesis of manoalide and seco-manoalide from an allylchlolide derivative was achieved by 6 steps in 56.4% overall yield by Pd (0) catalyzed coupling with CO and 2- trimethylsilyl-4-tributylstannylfuran followed by chemoselective oxidation of 2- trimethylsilylfuran with 1 O 2.