A new method for the preparation of 2, 2-dialkylcyclopropylamines

P Sulmon, N De Kimpe, N Schamp

Index: Sulmon, Paul; Kimpe, Norbert De; Schamp, Niceas Journal of the Chemical Society, Chemical Communications, 1986 ,  # 22  p. 1677 - 1678

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Citation Number: 2

Abstract

2,2-Dialkylcyclopropylamines have been prepared by a new synthetic method involving base-induced cyclization of P-chloroimines and subsequent hydrolysis. ... Cyclopropylamines are a well known class of compounds which can be prepared by Hofmann or Curtius rearrangement of the corresponding acid derivatives (cyclopropane carbox- amides and cyclopropane carbonyl azides) and by Beckmann rearrangement of the oximes derived from cyclopropyl ketones. ...