Synthesis and in vitro evaluation of imidazo [1, 2-b] pyridazines as ligands for β-amyloid plaques

F Zeng, D Alagille, GD Tamagnan…

Index: Adamczewska; Barker; Huddleston; Wood Synthetic Communications, 1996 , vol. 26, # 6 p. 1083 - 1096

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Citation Number: 8

Abstract

... Volume: Page: ... It is interesting to mention that the 6-methylthio IMPY derivative was reported to have a low retention to Aβ in AD patients.(26). Table 1. Inhibition Constant (K i Values) of Imidazo[1,2-b]pyridazines for Binding Synthetic Amyloid Plaques Aβ 1−40. ...