Preparation and cancer cell invasion inhibitory effects of C16-alkynic fatty acids.

K Ohashi, H Winarno, M Mukai, H Shibuya

Index: Ohashi, Kazuyoshi; Winarno, Hendig; Mukai, Mutsuko; Shibuya, Hirotaka Chemical and pharmaceutical bulletin, 2003 ,  vol. 51,  # 4  p. 463 - 466

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Citation Number: 16

Abstract

Five C 16-alkynic fatty acids (2—6) were prepared and examined their inhibitory effects on cancer cell invasion. It has been found that hexadeca-6, 8, 10-triynoic acid (5) and hexadeca- 8, 10, 12-triynoic acid (6) exhibit similar potent inhibitory activities with that of octadeca-8, 10, 12-triynoic acid (1) which was isolated from Scurrula atropurpurea (Loranthaceae).