(tmp) 2Zn⋅ 2 MgCl2⋅ 2 LiCl: A Chemoselective Base for the Directed Zincation of Sensitive Arenes and Heteroarenes

SH Wunderlich, P Knochel

Index: Wunderlich, Stefan H.; Knochel, Paul Angewandte Chemie - International Edition, 2007 , vol. 46, # 40 p. 7685 - 7688

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Citation Number: 204

Abstract

The directed metalation of arenas and heteroarenes is an important method for the functionalization of these scaffolds. Lithium bases have been used extensively to ortho- metalate various unsaturated systems.[1] The use of magnesium bases pioneered by Eaton etal.[2] has recently found renewed interest.[3] There are a number of useful synthetic applications of lithium magnesiates [4, 5] as well as mixed Mg/Li bases of the type ...