Derivatives of 5-Chloro-8-hydroxyquinoline

M Weizmann, E Bograchov

Index: Weizmann; Bograchov Journal of the American Chemical Society, 1947 , vol. 69, p. 1222

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Citation Number: 7

Abstract

Ethyl@-(Z-Hydroxy-5-chloroanilino)-crotonate.-A mixture of 10 g. of 4-chloro-2- aminopheno16 and 9 g. of ethyl acetoacetate was heated at 80” for four hours. Traces of iodine were found to catalyze the reaction. The solid product was filtered, washed with methanol and recrystallized from the same solvent. It formed slightly yellowish needles. mp 133-134; yield, 35%. Anal. Calcd. for C1.”, 4032jCl: N, 5.5. Found: N, 5.8.