Sodium borohydride-amberlyst-15 (H+): An effective reductor for hindered and unreactive ketones in aprotic solvent
JR Caycho, FG Tellado, P de Armas, J Juan…
Index: Caycho, Juana Robles; Tellado, Fernando Garcia; De Armas, Pedro; Tellado, Jose Juan Marrero Tetrahedron Letters, 1997 , vol. 38, # 2 p. 277 - 280
Full Text: HTML
Citation Number: 16
Abstract
The combination of sodium borohydride and amberlyst-15 (H+) in tetrahydrofurane is a powerful reductor for unreactive ketones. The reduction is fast, high-yielding and the work- up is extremely simple. Ketals, silyl ethers and other organic functions are not disturbed during the reduction.
Related Articles:
A new access to acyl-and aroyllithiums via lithium-tellurium exchange
[Journal of the American Chemical Society, , vol. 112, # 1 p. 455 - 457]
Tuning the reactivity of O-tert-butyldimethylsilylimidazolyl aminals towards organolithium reagents
[Synlett, , # 10 p. 1451 - 1454]
Solvent effects on the rates of solvolysis of pinacolyl derivatives
[Roberts, Donald D.; Hall, Edward W. Journal of Organic Chemistry, 1988 , vol. 53, # 11 p. 2573 - 2579]
Tuning the reactivity of O-tert-butyldimethylsilylimidazolyl aminals towards organolithium reagents
[Gimisis, Thanasis; Arsenyan, Pavel; Georganakis, Dimitris; Leondiadis, Leondios Synlett, 2003 , # 10 p. 1451 - 1454]
[Chemistry - A European Journal, , vol. 7, # 14 p. 3043 - 3051]