Synthesis and DPPH radical scavenging activity of 5-Arylidene-N, NDimethylbarbiturates

K Mohammed Khan, M Khan, M Ali, M Taha…

Index: Mohammed Khan, Khalid; Khan, Momin; Ali, Muhammad; Taha, Muhammad; Hameed, Abdul; Ali, Sajjad; Perveen, Shahnaz; Choudhary, M. Iqbal Medicinal Chemistry, 2011 , vol. 7, # 3 p. 231 - 236

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Citation Number: 14

Abstract

Twenty-four derivatives of N, N-dimethylbarbituric acid 1-24 were screened for their DPPH radical scavenging activity. These compounds showed an excellent antioxidant activity. A structure-activity relationship has been discussed, while all the synthetic compounds were characterized by spectroscopic techniques and elemental analysis.