Organic fluorine compounds. IV. Synthesis and antifungal properties of 2-fluoro fatty acid amides

H Gershon, RL Rodin, R Parmegiani…

Index: Gershon,H. et al. Journal of Medicinal Chemistry, 1970 , vol. 13, # 6 p. 1237 - 1239

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Citation Number: 9

Abstract

Sumerous studies on the antifungal properties of fatty acids have been carried out. These were recently summarized by Gershon and Parmegiani2 who: tlso reported a study on the antifungal action of 2-fluoro fatty acids as compared with nonfluorinated fatty acids. Four factors which affect the antifungal activity of these compounds are concentration, chain length, pH of the medium, and presence or absence of materials such as serum albumin ...