Direct Synthesis of Organic Azides from Primary Amines with 2??Azido??1, 3??dimethylimidazolinium Hexafluorophosphate

…, N Tashiro, S Miyagawa, M Sando…

Index: Kitamura, Mitsuru; Yano, Masakazu; Tashiro, Norifumi; Miyagawa, Satoshi; Sando, Mitsuyoshi; Okauchi, Tatsuo European Journal of Organic Chemistry, 2011 , # 3 p. 458 - 462

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Citation Number: 23

Abstract

Various synthetic methods for organic azides have been developed.1 Among them, the nucleophilic substitution of organic compounds having a leaving group with an azide ion is a common method (Figure 1). Various alkyl azides are prepared by the reaction of sodium azide and alkyl halides/sulfonates, which are derived from the corresponding alkanols, whereas the synthesis of tert-alkyl azides are often not successful because of steric hindrance.9 Aryl azides are ...