Reversible 1, 4??Insertion of Pyridine Into a Highly Polar Metal–Carbon Bond: Effect of the Second Metal

…, TP Spaniol, L Perrin, L Maron, J Okuda

Index: Lichtenberg, Crispin; Spaniol, Thomas P.; Perrin, Lionel; Maron, Laurent; Okuda, Jun Chemistry - A European Journal, 2012 , vol. 18, # 21 p. 6448 - 6452

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Citation Number: 7

Abstract

Dihydropyridines (DHPs) serve as selective reducing agents,[1] are useful building blocks in organic chemistry,[2] and represent an important class of pharmacologically active compounds.[2d, 3] Transition-metal catalyzed 1, 4-selective hydrosilylations and silaborations of pyridine have recently been reported as two new methods for the synthesis of DHPs.[4] Remarkably, the hydrosilylation was found to be reversible. In general, the ...