Tetrahedron letters

[Bmim] BF 4 ionic liquid: a novel reaction medium for the synthesis of β-amino alcohols

JS Yadav, BVS Reddy, AK Basak, AV Narsaiah

Index: Yadav; Reddy; Basak; Venkat Narsaiah Tetrahedron Letters, 2003 , vol. 44, # 5 p. 1047 - 1050

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Citation Number: 162

Abstract

Epoxides undergo smooth ring-opening with aryl amines in 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim] BF4) or 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim] PF6) ionic liquids under mild and neutral conditions to afford the corresponding β-amino alcohols in excellent yields with high regioselectivity.