Facile access to biaryls and 2-acetyl-5-arylbenzofurans via Suzuki coupling in water under thermal and microwave conditions

AF Darweesh, MR Shaaban, AM Farag, P Metz…

Index: Darweesh, Ahmed F.; Shaaban, Mohamed R.; Farag, Ahmad M.; Metz, Peter; Dawood, Kamal M. Synthesis, 2010 , # 18 p. 3163 - 3173

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Citation Number: 16

Abstract

Abstract The phosphine-free Suzuki-Miyaura carbon-carbon cross-coupling reactions of activated and deactivated aryl halides and 2-acetyl-5-bromobenzofuran with various aryl-or heteroarylboronic acids were investigated. A benzothiazole-based palladium (II) complex was used as a precatalyst for the reactions under both thermal and microwave conditions in air using water as a solvent.

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