Studies on quinones. VII. Synthesis of some benzo [b] thiophene??4, 7??diones

VM Ruiz, R Tapia, J Valderrama…

Index: Ruiz, V. M.; Tapia, R.; Valderrama, J.; Vega, J. C. Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1161 - 1164

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Citation Number: 17

Abstract

Abstract The synthesis of methyl 4, 7-dihydro-4, 7-dioxobenzo [b] thiophene-2-carboxylate (20) based on the reaction of methyl mercaptoacetate with activated 1, 4-benzoquinones is described. Methyl 4, 7-dihydro-4, 7-dioxo-5-hydroxybenzo [b] thiophene-2-carboxylate (24) and its corresponding methyl ether 26 were obtained through a Thiele-Winter acetoxylation on 20. On the basis of the properties of methyl 4, 7-dihydro-4, 7-dioxo-6-methoxy-benzo [b ...